CellFree - Resources

Green Tea (Camellia sinensis)
Green tea promotes healthy tissues on many levels: it has direct antioxidant activity; increases the activity of antioxidant enzymes; supports the production of immune cells; supports detoxification of detrimental agents within the body; supports glucuronidation of estrogen; and inhibits the activation of proteins in the signaling pathways that may initiate unwanted cellular changes. The green tea in CellFree also supplies 10 to 20 mg of caffeine per softgel (one 6 oz cup of coffee contains 100 mg), which is associated with its positive biological activity. In fact, a study on premenopausal women showed that caffeine-containing green tea appeared to favorably affect hormone levels associated with breast health. The caffeine in green tea does not appear to produce a stimulant effect, even in those quite sensitive to caffeine; this is believed to be due to the theanine content of green tea.

D-Limonene
This exciting compound supports the metabolism and detoxification of hormones and other substances that can affect cellular DNA and cell growth. D-limonene is a widely distributed, natural, and non-nutritive monoterpene found in small amounts in a variety of foods (e.g. 8 oz orange juice contains 19 mg) and volatile oils—particularly citrus oils.

Lycopene
The lycopene in CellFree is highly bioavailable. Lycopene is the carotenoid that gives tomatoes their red color and it may be an even more potent free radical quencher than beta-carotene. Lycopene imparts multiple health benefits to tissues, glands, and organs susceptible to excess oxidative stress and cellular changes.

Turmeric (Curcuma longa)
Curcumin from turmeric has also been shown to support cell health and a normal cell life cycle through its antioxidant enhancing properties, and its influence on cell signaling pathways.

1. Ahmad N, Feyes DK, Nieminen A, et al. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst 1997;89:1881-86.
2. Ahmad N, Gupta S, Mukhtar H. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells. Arch Biochem Biophys 2000;376(2):338-46.
3. Jiang MC, Yang-Yen HF, Yen JJ, et al. Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. Nutr Cancer 1996;26(1):111-20.
4. Karas M, Amir H, Fishman D, et al. Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cell lines. Nutr Cancer 2000;36(1):101-11.
5. Khafif A, Schantz SP, Chou TC, et al. Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. Carcinogenesis 1998;19(3):419-24.
6. Nagata C, Kabuto M, Shimizu H. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nutr Cancer 1998;30(1):21-24.
7. Vigushin DM, Poon GK, Boddy A, et al. Phase I and pharmacokinetic study of D-limonenein patients with advanced cancer. Cancer Chemother Pharmacol 1998;42:111-17.

Note: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Please consult your licensed or certified health care practitioner for medical advice.